Quality control of translation is crucial for maintaining cellular and organismal homeostasis.Obstacles in translation elongation induce ribosome collision, which is monitored by multiple sensor mechanisms in eukaryotes.The E3 ubiquitin ligase Znf598 recognizes collided ribosomes, triggering ribosome-associated quality control (RQC) to rescue stall
IntroductionThe aim was to explore the neural network prediction model for Cardigan suicide based on back propagation (BP) and multilayer perceptron, in order to establish the popular, non-invasive, brief and more precise prediction model of suicide.Materials and methodData were collected by psychological autopsy (PA) in 16 rural counties from thre
Isoniazid induced sideroblastic anemia is a rare event.We report case of a 45 year old Caucasian women with Grooming Kit development of severe anaemia 4 month after introduction of Isoniazid as part of Tuberculosis treatment.While haemoglobin fell to 47 g/L and erythrocyte count to 1.5 G/L, reticulocytes were very low (reticulocyte production index